Bd Accusprayв ў Nasal Spray System Choose stoppers that suit needs across therapeutic areas. bd's collection of literature on industry and on our offerings gives you information you can use to continue striving for excellence. using the bd accuspray nasal spray system, healthcare providers can provide accurate, user friendly nasal drug spray delivery for a positive patient. Bd accuspraytm • disposable system for nasal administration of vaccines • non reusable, single use nasal sprayer for monodose or bidose administration • bd accuspraytm complies with iso 10993 11; usp <381>2, <660>3,6, <661>4; ph eur 3.1.85, 3.2.16, 3.2.92 spray nozzle spray nozzle valve stopper fm257 dose divider (optional) up to 0.1ml.
Bd Accusprayв ў Nasal Spray System Drugs may be swallowed into the oral cavity or gastrointestinal tract along the bottom of the nasal cavity and are absorbed by the gastrointestinal mucosa. drugs also enter the lungs through inhalation and are absorbed into the systemic circulation. similarly, many drugs are absorbed by the lymphatic system. figure 2. The intranasal vaccine delivery system induces both mucosal and systemic immune response, which avoids entry of pathogen in all mucosal routes. multiple delivery systems are being explored (both developmental and clinical phases) and can open the door for practical development of nasal vaccine delivery systems. 1. Again, the used of an appropriate delivery system to enhance the vaccine – mucosa interaction is crucial to improve the vaccine outcome. endocine is a delivery system specifically developed for intranasal vaccines. it is a lipid based (monoolein and oleic acid) dispersion with particles less than 100 nm (falkeborn et al., 2013). Introduction. intuitively, the nose offers easy access to a large mucosal surface well suited for drug and vaccine delivery. however, factors related to the nasal anatomy, physiology and aerodynamics that can severely limit this potential, have historically been challenging to address.
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